If you are looking for a podcast that can make you laugh out loud just listen out to IRL Talk. Faith and Jason both seem hilarious on their own but the dynamic between the two is hysterical.
Beyond their wit and delightfully contagious laughter it is also an interesting look at pop culture and technology. The majority of the podcasts that I listen to analyze technology from a very high level perspective. On IRL Talk it is a fun, down-to-earth discussion between to friends that occasionally talks about initial impressions on new technologies alongside of culture, movies, and television.